Italian #39: Maria Gaetana Agnesi

Although Maria never made any breakthrough or major contribution to math, she was the first European woman to publish a textbook (what they would call a handbook then) which focused on differential and integral calculus. I have little idea what those are because I only got as far as pre-Calculus in high school. She was also the first woman to be appointed as a Mathematics Professor at a European University, the University of Bologna.